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KMID : 0377619730240060629
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Korean Jungang Medical Journal
1973 Volume.24 No. 6 p.629 ~ p.634
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Study on Revaccination Method of B.C.G
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李性寬/Lee, Sung Kwan
申在鉉/宋善佑/申泰圭/Shin, Jae Hyun/Song, Sun Woo/Shin, Tae Kyu
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Abstract
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It is a well known that upon reinoculation of B.C.G. there is a severe local reaction at the site of inoculation, called the Koch. phenomena.
We intend to explore a new method of inoculation which does not invoke an undesirable reaction; therefore we may increase public acceptance of B.C.G. inoculation.
So we tried the oral administration of B.C.G. instead of inoculation. The results of the study are as follows:
1. Tuberculin allergy after oral administration of B.C.G. was lower in rate and weaker-in reaction than those of the inoculation.
2. There is no any side reaction with oral administration of B.C.G.
3. Taking into account of the fact that the positive rate was increased with advancing time after oral administration of B.C.G. it would be possible to expect improvement of the reaction by increasing the dose of B.C.G.
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